Gene information
Official symbol SMARCA4
Official full name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Gene type protein-coding gene
Chromosome19p13.2
Alias symbolhSNF2b; BRG1; BAF190; SNF2; SWI2; SNF2-BETA; SNF2LB; FLJ39786
Previous symbolSNF2L4
Gene familyBromodomain containing; BAF complex; PBAF complex; GBAF complex
Resources
Entrez Gene 6597
HGNC HGNC:11100
Ensembl ENSG00000127616
Vega OTTHUMG00000169272
UCSC uc060tnr.1
GO terms: 40 records
GO Description Category LogP Number of genes Detail
GO:0001221 transcription coregulator binding GO Molecular Functions -4.88806294 16 More
GO:0001558 regulation of cell growth GO Biological Processes -19.1123936 65 More
GO:0001650 fibrillar center GO Cellular Components -1.52869703 5 More
GO:0001654 eye development GO Biological Processes -3.29977134 15 More
GO:0003682 chromatin binding GO Molecular Functions -2.81388432 19 More
GO:0007423 sensory organ development GO Biological Processes -8.10586983 29 More
GO:0008134 transcription factor binding GO Molecular Functions -5.50998540 50 More
GO:0016462 pyrophosphatase activity GO Molecular Functions -2.27389045 21 More
GO:0016817 hydrolase activity, acting on acid anhydrides GO Molecular Functions -2.25488010 21 More
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides GO Molecular Functions -2.25488010 21 More
GO:0016922 nuclear receptor binding GO Molecular Functions -4.35310017 9 More
GO:0017111 nucleoside-triphosphatase activity GO Molecular Functions -1.71072310 18 More
GO:0030111 regulation of Wnt signaling pathway GO Biological Processes -7.94227486 39 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030177 positive regulation of Wnt signaling pathway GO Biological Processes -5.04077211 10 More
GO:0030308 negative regulation of cell growth GO Biological Processes -7.25826751 14 More
GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway GO Biological Processes -4.62709399 7 More
GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway GO Biological Processes -6.62830099 7 More
GO:0034654 nucleobase-containing compound biosynthetic process GO Biological Processes -2.18989332 18 More
GO:0040008 regulation of growth GO Biological Processes -30.7609323 104 More
GO:0043010 camera-type eye development GO Biological Processes -3.41918860 14 More
GO:0045580 regulation of T cell differentiation GO Biological Processes -7.18541630 25 More
GO:0045582 positive regulation of T cell differentiation GO Biological Processes -5.99210992 10 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045926 negative regulation of growth GO Biological Processes -11.4342361 38 More
GO:0047485 protein N-terminus binding GO Molecular Functions -1.43728137 4 More
GO:0048880 sensory system development GO Biological Processes -3.47450215 31 More
GO:0050681 nuclear androgen receptor binding GO Molecular Functions -2.12450567 3 More
GO:0051052 regulation of DNA metabolic process GO Biological Processes -4.01973325 42 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
GO:0051091 positive regulation of DNA-binding transcription factor activity GO Biological Processes -17.7436786 49 More
GO:0060765 regulation of androgen receptor signaling pathway GO Biological Processes -3.49817224 4 More
GO:0060766 negative regulation of androgen receptor signaling pathway GO Biological Processes -4.62139945 4 More
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding GO Molecular Functions -8.00802452 40 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0140297 DNA-binding transcription factor binding GO Molecular Functions -6.94737226 46 More
GO:0150063 visual system development GO Biological Processes -3.59465978 31 More
GO:1902893 regulation of miRNA transcription GO Biological Processes -10.5909336 18 More
GO:1902895 positive regulation of miRNA transcription GO Biological Processes -9.50703189 15 More
GO:1903037 regulation of leukocyte cell-cell adhesion GO Biological Processes -23.2079690 66 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04714 Thermogenesis KEGG Pathway -1.67288051 7 More
hsa05225 Hepatocellular carcinoma KEGG Pathway -5.07719186 21 More
Drug-Gene interaction
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Related drugs: 7 records
Related studies: 3 records
Molecular factor Omics type Application Objective MI type Reference
cg17218495 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Nakatochi M et al. Clin Epigenetics. 2017
NM_001128849.3:c.4521-5330G>T genomics myocardial infarction[diagnosis] myocardial infarction Yang XC et al. Thromb Res. 2010
NM_001128849.3:c.4521-5330G>T genomics acute myocardial infarction[diagnosis] acute myocardial infarction Chen QF et al. Anatol J Cardiol. 2018
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